Continuity mistake: When Raj and Leonard are sitting on the couch, Leonard is holding Watchmen and Lost in Space in his left hand and Young Sherlock Holmes in his right. In the very next shot when Leonard turns his head after Raj speaks, Watchmen has disappeared.
Factual error: Maybe I'm wrong but I've had the dislocated shoulder experience and shouldn't hers be in a sling at her side not across her front right to left? This just seems odd.
Factual error: Sheldon and the team are league bowling and have a match with Will Wheaton's team. They are bowling on lanes 2 and 3. In league bowling, you have to bowl on lanes that start with an odd number because the ball return is shared between those lanes. In league bowling, you take turns with each lane so that any differences in the lanes evens out, and this lane layout wouldn't allow that.
Continuity mistake: When Sheldon sneaks into Leonard's bedroom while Leonard and Penny are sleeping, Penny has her arms out over the blanket and Leonard has his on his pillow in front of his face. When Sheldon leans over Penny only her hands are on top of the covers and Leonard's are tucked under his pillow.