Revealing mistake: After Johnny joins Roy in the ambulance and the patient flatlines they continue to Rampart, and when Brackett asks 51 for a strip, if we look out the window that's beside Johnny, we can see GlamourTrams in the distance. And when Roy says, "Isopeterenol drip, 10-4," we can see GlamourTrams right outside the window. They are driving around Universal's lot while shooting the footage inside the ambulance.
Visible crew/equipment: At the start, when Johnny is telling The Stewardess about the underwater rescue and in following shots, the outline of the lavalier mic wire and the dark strap (that holds the transmitter) around Johnny's waist are visible on the back of his shirt, and the mic transmitter is visible on the front, left side of his shirt, above his belt.
Visible crew/equipment: At training center, after 18's guy falls into the trench with the sulfur trioxide, as they're removing his turnout coat just as Roy opens the drug box, seen behind Marco are four crew members who are near the tanker with the sulfur trioxide, past the trench.
Continuity mistake: When Dixie shows Johnny the newspaper, Johnny reads the ad aloud which states, "Wanted, 1925 Paige fire truck, $25,000, if in mint condition," and Johnny says that it is exactly what the ad submitter wants. The "it" being Roy and Johnny's refurbished fire truck. The problem is that in 3x2, "The Old Engine," when Johnny and Roy are telling Chet and Marco about their purchase, Johnny says that it's a 1932 Dennis, and when they're looking it over, the blue "Dennis" emblem is attached to the hood of the engine.
Continuity mistake: While Roy and John are still aboard the Coast Guard helicopter during the cliff rescue at Catalina Island, when the chopper's on scene, in the overhead shot from inside the chopper, we can see where the victim is lying on the rocks, however, in the next shot from ground level, the victim is now lying on the other side of the jutting rock.
Continuity mistake: When Squad 51 arrives at the training center, Johnny's turnout coat is open and we see that he's only wearing an undershirt, but when it's 18's turn at the sulfur trioxide, as Johnny's putting on his air mask he's wearing the blue uniform shirt under his turnout.
Deliberate mistake: When Johnny and Roy are on the Coast Guard copter, responding to 'victim down at cliffs at Catalina Island', there are four closeups of the guys looking out the windows which are flipped shots - note their uniforms are backwards, the paramedic patches are on their right sleeves instead of their left.