Deliberate mistake: The Globe Theatre is shown staging performances at night. In actuality, they performed during the day, when there was enough light, since this was pre-electricity. This was done both to make the climax of the episode scarier and because they shot on location in the real Globe, which still shows its plays during the day, and thus they didn't have a lot of time to shoot during the day there.
Continuity mistake: Among the various contents of the Black Archive are visible several objects that shouldn't be there, because it is impossible for U.N.I.T. to have acquired them. In particular: A detonation pack from "Planet of the Ood", set in the 42nd century, a few thousand years in the future. The Supreme Dalek's shell from "The Stolen Earth"/"Journey's End" - it was shot and killed by Jack Harkness, destroying the shell. The restraint chair from "The End of Time", last seen on the Vinvocci's ship. The makeshift sonic screwdriver built by the alternate Amy from "The Girl Who Waited", since that version of Amy was wiped from existence. A different explosive carried by Gregor Van Baalen in "Journey to the Centre of the TARDIS", which is both set in the future and involves a complicated situation in which the events ended up technically not happening.
Continuity mistake: The registration of Milo and Cheen's car is shown on the computer screen and stated aloud as "4-6-5-◊-6." However, there is a shot of Martha and Cheen looking out the window where the car's registration sticker is visible, showing a different registration: "9-9-6-γ-1." (00:13:15)
Continuity mistake: When the Sphere Chamber is first shown, there is a rolling staircase set up just below the Sphere. Rajesh Singh is shown climbing the staircase and nearly touching the Sphere. However, when the room is next seen, when Raj hears that the Doctor is coming and walks up to look at the Sphere again, the staircase has vanished. Later, when the Doctor and Jackie are shown into the room while Yvonne gives them the Torchwood tour, the staircase is still missing, and it's more obvious that it is no longer in the room. It does not reappear for the remainder of the two-parter.
Other mistake: Shortly after everyone arrives on the Vinvocci ship, when the Vinvocci and the Doctor run through the door on their way to the flight deck, the Doctor comes back to get Wilf, who didn't initially follow because he was mesmerized by the sight of the Earth from orbit. It's obvious that David Tennant went just behind the door and paused briefly before coming back into the room, which is not what the Doctor is supposed to be doing. (00:16:00)
Continuity mistake: During the scene on the hospital roof, when the Doctor is telling off the Atraxi while simultaneously choosing a tie out of several he stole from the locker room, the number of ties draped around his shoulders and the position of his hands changes between shots. (00:52:35)
Continuity mistake: In this episode's TARDIS scenes, the yellow padded seat is positioned so that it's on the side of the console closer to the door, so people sitting on it are facing away from the door. In all other episodes featuring this version of the console room, the seat is positioned on the side of the console opposite the door.
Factual error: The opening shot of the episode reuses the zoom-in from orbit originally used in "Rose." The North Pole is sunlit, as it would be at the height of summer. "The Runaway Bride" takes place on Christmas Eve, four days after the Northern Hemisphere's Winter Solstice, when the Pole would be facing away from the Sun, in darkness. In fact, this was the second Christmas special in a row to make this mistake, after "The Christmas Invasion." (00:00:05)
Continuity mistake: When the robotic Christmas tree attacks Rose, Jackie and Mickey in the Tylers' flat, it barrels through the internal window and destroys a supporting pillar separating the living room from the main hallway. Later in the episode, the pillar is seen intact. (00:13:30)