Factual error: When Dr. Cameron's agoraphobic patient goes into cardiac arrest at home following the surgery, she tells House to get the paddles ready. House, while performing CPR is talking on the phone with the patient's lawyer, informing him that patient has PEA (pulseless electrical activity) on the cardiac monitor, but Dr. Cameron defibrillates the patient anyway, restoring the heartbeat. Defibrillation is not indicated for PEA, it will not restore the pulse and might send the patient into vFib.
Factual error: When House is looking over his whiteboard of symptoms for the swimming patient, the symptom "Intercranial Hemorrhage" is shown on the board. However, this is an error. The correct term is "Intracranial Hemorrhage." Anything inside the head is referred to as "intra" not "inter." This is a common mistake for laypeople, however the highly trained and knowledgeable Dr. House should not have made that error. (00:31:25)
Factual error: House's team listed the potential offending organisms of the infection as "MRSA, H. Flu, VRE, and pseudomonas." House then suggests Vancomycin and Aztreonam. Vancomycin only covers gram (+) organisms and Aztreonam only covers gram (-) organisms. VRE is a gram (+) organism, thus it would not be covered by Aztreonam. VRE stands for vancomycin resistant enterococcus, thus it would not be covered by Vancomycin either. House's team therefore failed to cover for an offending organism that could have caused the infection during their initial differential. (00:09:10)
Character mistake: Episode 6.12, Moving the Chains: Marcus tells House that he and Eric were arrested for stealing a car, he was 16 and Eric was 14. He also says that his brother never did anything criminal after that. In season 1, we were told that Eric was 16 when he was arrested for stealing a car.
Factual error: House is playing 'Metroid: Zero Mission' on his Gameboy at various times. The Metroid series does not feature space monkeys, nor are there distinct levels. The sounds coming from the game in the show do not match it in real life, and Samus morphing into a ball is most definitely not a failure state.
Continuity mistake: As House describes the lady's symptoms, in the front shot Chase has a small book/pamphlet in his hand. The camera changes to a side shot in the middle of House's description and suddenly the book is on the table and no longer in Chase's hand. This happens right in the middle of House's line and Chase doesn't make any quick movements to account for this discrepancy.
Continuity mistake: House is about to inject Ezra Powell (Joel Grey) with what is supposedly a lethal dose of morphine. In the shots where they pan out to show House addressing the room at large, the syringe is very full, almost completely. When they zoom in on House holding the syringe, it is only filled a fraction of that much - maybe a quarter to a third. This doesn't happen just once, but every time they switch between shots.
Visible crew/equipment: In the scene where House and Allison are walking down the stairs, they round a corner and we see a dolly shot down a short hall with a glass wall in front. During this shot, a camera, cameraman, and dolly are visible in reflections on the glass. (00:08:20)
Factual error: In episode 414, "Living the Dream," the patient Evan is given a nerve function test. We see Kutner and Taub performing the test by puncturing Evan's legs with needles. Modern nerve function tests actually rely on electrical impulses from a small computerized device, with no needles necessary.