Plot hole: The CSIs catch a murder suspect putting down a drink can when reviewing security footage of a robbery, and immediately realise they didn't see it at the scene so assume one of the first cops on the scene must have removed it. Thing is though, the murderers shot out the security camera before the actual shooting occurred, meaning there was loads of time off-camera for the killers to take the can with them, but the CSIs never even consider this - they jump to the conclusion a cop took it even though there's no actual evidence for that.
Audio problem: When Mac and co. enter the basement of the house in Queens (the one where the third woman was found) the record player lifts off its needle and moves to another spot on the record, cutting off the sound for a second. However, the music starts again slightly before the needle hits the record.
Continuity mistake: Stella prints the pictures of 6 suspects. Mac takes them all, holds one up and says : "That's the man we're looking for." But only 5 pictures comes out of the printer - and the picture of the suspect isn't among them. Mac holds up the picture of an black guy with afro hairdo - the suspect is white with rumpled black hair. Where does his picture come from ? (00:07:10)
Plot hole: At the end of the episode, Stella and the others determine their rape suspect is guilty because they confirm the tree sap on his clothes transferred to the victim's underwear. That transfer should have been discovered, if not blatantly obvious, during their initial processing of evidence.
Continuity mistake: In autopsy, Mac, Stella and Dr. Hawkes M.E. are examining a skeleton that was found on a bus. As Mac asks about cause of death, Sheldon points to a skull fracture that is evident above the skeleton's left eye, a fracture that wasn't there when the skeleton was first discovered sitting in the back of the bus.
Continuity mistake: At the beginning of the episode when Mac & Stella first look in The Box at the beach, Lucas' head is at the back right corner of The Box with a leg wedged from the back left to the back right corner and the back quite uppermost. When they open The Box in the lab and go to remove it with the doctor, the head is in the front right corner with arms and legs visible uppermost like the body has been rotated, but it would not have been touched or removed from The Box by that point. The second arrangement of the body is shown in the flashbacks throughout the episode.