Continuity mistake: When Monk attempts to steal the truck at the gas station and grabs the sleeping driver's keys, he drives the truck in circles and then stops. When he stops, the truck is exactly parallel to the end of the concrete slab where the gas pumps are located. However, when the police arrive, the truck is now at a different angle with the back of the truck now being closer to the end of the concrete slab than the front. The gas station attendant would not have moved the truck himself as the police would have told him not to touch anything at the scene.
Plot hole: *Spoilers* Monk and Stottlemeyer cook up an ingenious plan to make Monk appear dead, but how the fugitive Monk acquires his regular clothes (in place of Mitch's uniform), the bullet-proof vest and the gun is not addressed. The police are watching Monk's apartment, Disher is watching Natalie and Julie, and Sheriff Rollins is watching Stottlemeyer, leaving us to wonder just how they managed all this right under their fellow cops' noses. (00:43:00)
Continuity mistake: When Natalie comes into her house and realizes Monk is there (because he's reorganized the refrigerator), the first camera shot after she closes the refrigerator door shows a Tupperware container with a blue lid just to the right of the refrigerator (facing it) that is slightly turned so that is is not parallel to the refrigerator's side, and then just to the right of the container is a blender with the top lid off. When Randy shows up moments later, there is a camera shot that shows that the Tupperware is now square with the refrigerator's side, and it appears to be a different Tupperware than the first shot, as it looks bigger and appears to have more stored inside of it and it does not appear to have a blue lid. Also, the blender now has the top lid on it. In a third shot, the blender has now moved to the right at least 12 inches, which is confirmed while Natalie is preparing the smoothie: it can be seen that it has moved from its previous position and the blue topped Tupperware has returned. Finally, when Natalie starts to prepare the smoothie, the top of the blender is off and it is not ever seen that she removed the lid herself.
Continuity mistake: The needle Monk finds in the campers' sewing kit threads itself instantaneously between takes. He finds the spool of orange thread, and in the very next shot, tho there's absolutely no indication of any time passing, he's holding the already-threaded needle. (00:22:00)
Continuity mistake: When Monk is shot he staggers back against the wooden railing - his arms are barely a foot above it, no way he'd overbalance and fall over. In the angle from behind the railing only comes up to about his waist, and he promptly topples over it.
Plot hole: The D.A. says that ballistics show that the bullet came from Monk's gun. The simplest thing to do would be to look at the gun, they'd know that it hadn't been fired and was full. With Monk's OCD we know it was cleaned, and the sheriff came in right after, so Monk couldn't have reloaded it. Yet they overlook all of this.
Continuity mistake: When Mr. Monk is first arrested by the Sheriff, his arms are fully extended for the entire time that he is lying face down on the floor and his head is turned to one side. However, later on, Mr. Monk explains on the phone to Captain Leland Stottlemeyer how the Sheriff framed him. While the Sheriff is changing the gun barrels during Mr. Monk's explanation, you now see Mr. Monk with both of his hands behind his head and his head is now face down on the ground.