Continuity mistake: When Monk is shot he staggers back against the wooden railing - his arms are barely a foot above it, no way he'd overbalance and fall over. In the angle from behind the railing only comes up to about his waist, and he promptly topples over it.
Continuity mistake: In this episode, Randy says that his uncle left him a farm in his will. In the episode "Mr. Monk Gets Cabin Fever", Randy stated that all of his uncles are deceased. Kind of hard to be given a farm from a guy who's been dead since Season 3.
Continuity mistake: "Nationwide Airways" is the name of the fictional carrier used in the episode, and it even has its own logo and livery. Yet in the exterior shot of the plane pushing back from the gate, it has suddenly transformed itself into a Delta Air Lines plane. It also looks like a 1990s Delta plane while it is taking off. (00:13:05 - 00:15:00)
Continuity mistake: When Kloster hands Natalie the cup of lemonade, the cup is about two-thirds full. In the shots from the right side of the car, the level is about the same, but in the shots from the left side of the car, it's almost full. (00:22:30 - 00:23:30)
Continuity mistake: In the lab scene near the end, when Monk has the electric wheel chair, Natalie is holding the bottle of pills in her right hand and the drink in her left hand when she gets up from the seat. In the next shot she is holding the drink in her right hand and the pills in her left.
Continuity mistake: When Monk and Brian face off with the bear, there are two tree stumps in between. When the camera is on the bear, he's close to the stumps and Monk and Brian are several feet away. In the reverse angle shot, though, Monk and Brian are close to the stumps and the bear is several feet away. (00:35:00)
Continuity mistake: In the first shot, when the captain is chatting on the computer and Monk is looking at him through the glass, the webcam we see is white and round. In the next scene, when Monk goes into the captain's office, the webcam is now gray and square.
Continuity mistake: When Monk is trying to get out of the Captain's car, Randy is trying to get his wheelchair out of the trunk. In the shots from the rear of the car, Randy is directly behind the vehicle. In the shots from the front, Randy is a few feet away. (00:18:00 - 00:19:00)
Continuity mistake: In "Mr. Monk On Wheels," after Monk gets out of the car, when he closes the door while standing on his unshot leg, he's facing the front of the vehicle. In the next shot, from behind the car, he's facing the rear of the vehicle without having turned around. (00:18:55)