Continuity mistake: While the Griffin family are at the Heimlich maneuver class, there is a scene where Stewie is talking to a doll and putting his clothes on. You can see that he has no shoes on but when he sticks his feet through the pant leg holes, shoes suddenly come out of the pants and he has his shoes on. (00:04:10)
Plot hole: Brian and Peter see Loretta and Quagmire having sex yet, they aren't sure who she's having an affair with. There's no way they couldn't have noticed it was Quagmire - the couch was facing the front door! And obviously Quagmire was on top of Loretta considering the fact that he leans up, says something, then she tells him to get back down here and finish.