Continuity mistake: On the inspector's boat Frank's wrists are handcuffed together with a railing between his arms to secure him in place. There is a very short chain between the cuffs, 4 to 5 inches at most. When he's pulled free by a rope from Elise's boat he starts 'climbing' the rope hand over hand. In one shot his hands are over a foot apart, he's obviously not wearing the handcuffs. When he gets onto Elise's boat his hands are cuffed once again, she shows him how to pick the locks to get the cuffs off.
Continuity mistake: Angelina has a stone as an earring. The next shot shows a dangling earring on the other ear, then the stone changes to the dangling earring in a future shot.
Continuity mistake: In the scene where the Italian police officer is taking Depp out of the lock-up cage at night, initially the officer's collar is turned up when he enters the cage. In the following close-up shot it is turned down, then again turned up when he applies the cuffs. (00:49:40)
Continuity mistake: As Frank walks on the roof, he is being filmed from different camera positions. The location and the number of chimney heads changes from take to take.
Continuity mistake: The two policemen on board the train take a picture of Franck, which is submitted to the British inspector via email. The inspector sees it on his computer screen and then prints it out. He then goes to the printer, but doesn't take the printout from the printer, but instead from the filing basket to the right of the printer - no-one's moved it there. The printout of Frank's face is there too quickly. It can't be done in such a short time.