Plot hole: Ambrose wants to spread a deadly virus so he can make loads of money selling the cure. To this end, he drops off infected Nyah in the middle of the city to get this going. For this to work it would have to a highly contagious airborne virus. However none of the characters are worried about being near Nyah after she is infected. Even the scientist who created it smuggled it out by infecting himself and then getting on very long commercial flight.
Continuity mistake: The tyres on the crotch rocket motorcycles they were riding kept changing from knobbly tyres to road slicks, back and forth depending on what terrain they were on. Easiest to see when Ethan skids on the road to avoid the white van - clear shot of slick tyres - then about 30 seconds later they're on the dirt, he skids into the old car and you can easily see that he's got off-road tyres front and back.
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