Continuity mistake: When Ryan Reynolds is between the two hospital beds, preparing to pull the plugs, there are three wires he grabs to our left (two white and one black). He yanks all of them out (along with another white one to our right) and no plugs remain in the red outlet cover on the wall. But in close ups, as the other agents are banging on the door, we see the lone black wire is still plugged in. (01:40:15)
Continuity mistake: When the police rush into the bathroom towards the end of the movie to capture Sir Ivy, you'll see that as they start to lift him up his left eye is completely covered in blood but when they lead him out of the room is eye is open with way less blood than before.
Continuity mistake: When Hugo is shot by Zoot, a spatter of blood comes from the exit wound, hitting the wall. When Zoot puts on Hugo's jacket, however, there is no bullet hole in the back of it when the bullet left.
Continuity mistake: As the exterior shot of Lake Tahoe advances, the cameras closes in on the roof of a hotel. Beyond, another hotel's facade is in shadow as the sun is behind it, off to our left. The shot sinks through the roof of the closer hotel so our view is now from within the penthouse, but now the facade of the second hotel is in full sun, the light is now coming from the left, but behind the camera. (00:18:40)