Continuity mistake: When Susanna gets into the cab to go to the mental hospital, she pushes the suitcase over and clearly sits on the left side of the cab (directly behind the driver), but in the following shots she is sitting on the right side, and looks out the right side passenger window.

Girl, Interrupted (1999)
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Directed by: James Mangold
Starring: Angelina Jolie, Brittany Murphy, Clea DuVall, Winona Ryder, Elisabeth Moss, Jared Leto, Jeffrey Tambor, Vanessa Redgrave, Whoopi Goldberg
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Trivia: Marilee Rush's "Angel of the Morning", featured in the film's soundtrack, was written by Angelina Jolie's uncle, Chip Taylor.
Question: Why did Polly get a panic attack in the middle of the night?
Answer: If you listen to her yelling when they try to subdue her, she yells out "I'm ugly". This is most likely stemming from earlier when Angelina's character makes a comment about Polly never finding love because of the way she looks.
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Answer: Polly freaked out because she had seen Suazanna kissing her boyfriend earlier that day. Polly realised that is something she will never have.