Howard Hughes: You have called me a liar and a thief and a war profiteer.
Ava Gardner: ...You can't buy me, Howard, so stop trying. Don't buy me any more diamonds or sapphires or any other damn thing. You can buy me dinner.
Howard Hughes: I feel like a little adventure.
Katharine Hepburn: Do your worst, Mr. Hughes.
Howard Hughes: I care very much about aviation.
Chosen answer: Hughes has obsessive compulsive disorder. He washes his hands so often, and so intensely, that he's literally worn away his skin. This is common with OCD sufferers.