Factual error: After the scene where they fall over the waterfall, and go through what they have left of the equipment. Bill, the Latino doctor, holds up the CD-reader from a desktop computer and says that the hard drive is broken, which would be OK if he actually had the hard drive present. (00:34:35)
Visible crew/equipment: Right before they go over the waterfall, you can see the film crew in the mist.
Factual error: Crocodiles do not hunt by smelling blood like sharks do. They have keen eyesight and would also be attracted by the splashing water.
Continuity mistake: After the scene where the first Umbrella Corp. employee gets eaten, the rest are discussing what just occurred. All their clothes appear to be dry. They just scrambled to get out of the river and should all be soaking wet.
Audio problem: Just after the captain of the other boat (Bill's friend) breaks the bottle, and looks over the side, you hear a voice say "What the hell was that" although the guy's mouth doesn't move, also the voice sounds more like Bill's low voice than this guy's Australian-sounding accent.
Continuity mistake: When Cole is lost in that underground cave, first he has a silver torch with a handle, and then when he meets Tran he has a thick chunky one, then it changes back to the silver one.
Revealing mistake: When Bill sets the tribe's hut on fire, everything lights up instantly and within moments the whole thing is alight, although it takes longer than that for a whole hut that size to set in flames.
Continuity mistake: The woman who falls off the boat is pulled underwater by the crocodile. When she is rescued, there are no signs of bite marks or any other trauma.
Factual error: The movie is located on Borneo and the hunters at the beginning of the movie are hunting a tiger. Though there are tigers in Indonesia there are no tigers on Borneo.