Trivia: When Adams and Franklin are arguing about whether to remove the slavery clause from the Declaration, Adams' line about never being forgiven by posterity is actually part of a quote by his cousin Sam. The entire line is "If we give in on this issue, there will be trouble a hundred years' hence. Posterity will never forgive us." The part about trouble in a hundred years was deleted because Sherman Edwards and Peter Stone were afraid audiences would think, with the power of hindsight, that they made the line up, instead of it being from an actual historical quote; the prediction Sam Adams made missed the Civil War by just 15 years.
Trivia: Ron Holgate did all of his own horseback riding, with the exception of the trick mount at the end of "The Lees of Old Virginia;" prior to this film, Holgate had never ridden a horse.
Trivia: Thomas Jefferson's wife, Martha, died ten years after their marriage - a full nineteen years before Jefferson occupied the White House; the Martha Jefferson listed as First Lady was the pair's daughter.
Trivia: In one of the biggest coincidences in American history, John Adams and Thomas Jefferson both died on the 50th anniversary of the adoption of the Declaration of Independence. This fact was never included in the play, because Sherman Edwards and Peter Stone both knew that no one would believe it.