Factual error: Shortly after the crash, when Chuck is in the raft, one of the engines continues to run even though it is half submerged in water. The engine would not have exploded like it did, rather, it would have just stopped running as soon as it became disconnected from its fuel source and flooded with water.
Factual error: In the scene where a boy runs on the streets of Moscow, he passes by the famous Moscow landmarks: St Basil's cathedral, Moscow State University, Big Stone Bridge etc. In reality it would have taken him a good four or five hour run to do that.
Factual error: When Chuck finds the dead pilot, he buries him and marks his death as 1995, so we can assume the crash was in 1995. His Jeep is at least a 1997 or later model, as it is a second generation Cherokee which has newer grille and taillights.
Factual error: Since the can that breaks through the net is an AMJ on the right side of the plane, they must be in either a DC-10 or a MD-11, as those are the only 2 planes that are wide enough to fit AMJs on the right side. However, when Hanks is in the ocean looking back at the plane, it shows the tail as it is sinking into the water. It shows enough of the tail (which has suddenly lost all its paint, in particular the FedEx logo) to determine that there is no intake on it, which signifies that they were on an AirBus. (00:28:00)
Factual error: As the plane hits the water, Hanks is pushed back into the cargo area. He travels through an empty passageway between rows of containers. Though this load configuration is possible, it is not used because it makes no sense. Furthermore, he finally stops against a container that reads AEE7480FX. This creates a couple more problems, as AEEs are not only no longer in use, but they were belly containers, with an angled side on the bottom that fits the contour of the bottom of the aircraft. There could not have been one of these on the topside of the aircraft. (00:26:05)
Factual error: On Tom Hanks' doomed flight, there is no smoke curtain or solid bulkhead in place. This is a heavy, opaque curtain or solid wall that separates the the topside cargo area from the seating area, designed to keep smoke from a fire away from the crew. On DC10/MD11 aircraft, this is generally a solid bulkhead, and on Airbuses a curtain. This plane should have been grounded until one was installed.
Factual error: When the FedEx packages wash up on the beach, all the contents are completely dry. Even the birthday card from the grandma is completely legible. FedEx does have waterproof packaging, I am sure, but those appear to be just regular boxes.
Factual error: Chuck's plane supposedly went down in 1995. During the early parts of the film, you see several Fed Ex aircraft with only two engines (one on each wing) which are Airbuses. Fed Ex had only a handful of these class of aircraft around 1995 making it impossible to see so many of them on the ground in Memphis, or in the Soviet Union for that fact at that time.