Continuity mistake: It was briefly stated in the second film that the T-Virus was created by Dr. Ashford to cure his daughter Angela and that the Red and White Queens were based on her. This movie contradicts that by suggesting that Dr. Marcus created the T-Virus to cure his daughter Alicia, and that the Red/White Queens were modeled after her. While the rest of the movie stays true to the continuity of the previous films, this rather obvious ret-con is still a major continuity gaff.
Alicia Marcus: I still own 50% of this company.
Dr. Isaacs: And what do you intend to do with that?
Alicia Marcus: You are co-owner of this corporation, but Wesker... Wesker is still an employee.
Wesker: I don't have to take your orders. My loyalties are with him.
Alicia Marcus: I know. Albert Wesker, you're fired.
Trivia: The film's production was quite troubled. A crewmember named Ricardo Cornelius was killed in a freak accident when he was crushed by a Humvee and a stuntwoman named Olivia Jackson was severely injured, with her face being "de-gloved" and sustaining may injuries and fractures which resulted in the loss of her right arm. Thankfully she survived and made a full recovery and the doctors were able to surgically mend her face and other injuries.
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