Continuity mistake: At the beginning when Indy is talking to Spalko, his hands keep alternating from being in his pockets to just resting at his sides between shots.
Continuity mistake: At Riley's Garage, when Troy and Chad are about to rummage through the junk looking for the radiator cap, Troy raises his arms and his boxers are light grey, but next shot when he lifts the truck's hood his boxers are black. It's also noteworthy to mention that during "Boys Are Back," young Troy is wearing patterned boxers, though all other clothing is identical. (00:53:45)
Continuity mistake: In the scene when Mary visits Hancock for the first time at his house, she arrives from the air and crashes down on the ground, after a discussion inside they both walk outside together and Mary is shown getting into a car. In the next shot shown from above the house the car has disappeared and they both fly into the air.
Continuity mistake: When Seth has been sliced by the blade, he spits blood that goes all over his face. It then cuts to Hoffman looking at him, then back to Seth, and now the blood on his face has gone. This happens three or four times. (00:05:10)
Continuity mistake: In an early part of the movie, Francis Tierney, Sr. is standing in front of a paper towel dispenser in a restroom with his son, Ray Tierney. The dispenser, which is visible over Francis Tierney's right shoulder, is at first full of paper towels, then empty, then full again. The paper towels are at first sticking out of the bottom of the dispenser, then they vanish.
Continuity mistake: During the duel between Miraz and Peter, when they call for a time out, Miraz is shown in the background walking back to his generals and stepping onto a raised area. A few seconds later, over Peter's shoulder, he again walks to the raised area and steps up (there's only one step). (01:44:55)
Continuity mistake: When Pepper is watching the television program about Stark Industries' stock troubles, after Tony's press conference, notice she has a wireless headset in her left ear. When Tony calls her down to the lab, the camera flashes back to Pepper and the ear piece is gone. (00:48:50)
Continuity mistake: During the police chase, the hub caps on Saul's police car keep appearing and disappearing throughout the whole chase.
Continuity mistake: During the street chase in Brazil, the time of day changes from night, to perhaps late afternoon/evening, to night again.
Continuity mistake: James takes off his tie to cover the cut on Kristen's hand, but when they run outside to escape in the car James is wearing his tie again, then after the failed escape they run back inside the house and James tie is missing. In another scene Kristen goes into the woods to look for James and falls into a ditch, then as she climbs out the tie is missing from her hand, but the next scene it's back in place.