Plot hole: In the Redstar mainframe, we are told that the floor of the vault will trigger the alarm if it receives more than 0.25 seconds of contact (apparently even with the security checks). What would be the point of the bosses going through all of those security measures if they would just set the alarm off anyway? Surely once the girls have faked the fingerprint and retina scans, they don't then need to flip across the floor! (00:33:55)
Plot hole: When Wolf and Tony find Virginia in the Huntsman's tree house, she tells them that he chained her up, so she can't go downstairs and open the door from the inside. However, after Wolf climbs her hair and enters through the window, the two of them walk down the stairs without any chains stopping her. They couldn't have cut her free with the magic ax because Tony was holding it, and he was downstairs by the door.
Plot hole: When Tim Robbins is floating away in space his wife could have easily saved him. She could go out a little further, use the grappler to catch her husband, then use the fuel she has remaining to halt their acceleration towards the planet and return them partway to the necessary orbital altitude/velocity to rendezvous with the resupply module. Then, Gary Sinise could come out partway to them using his thrusters, Connie could shoot the grappler out to him, and he could reel both Connie and Tim Robbins back in to the resupply module.
Plot hole: The attack on Israel scene leaves one important question: How would it have been possible for the bad guys (the Russians, or Arabs, or whoever) to stage such a massive surprise attack without being discovered ahead of time? Anyone who is knowledgeable in modern warfare would know that an operation of that scope would require a considerable amount of logistical preparation that could not possibly go unnoticed, especially considering the capabilities of modern spy satellites.
Plot hole: The virus ravaged Nyah is making her way to a cliff to kill herself when Ethan sends his buddies to save her. There is no way that the flight to her location would have taken that long unless John Polson decided to take Ving Rhames for a guided tour of the Sydney skyline first just in case he missed any of it. It's just a couple of minutes flight time for a helicopter at full throttle.
Plot hole: After witnessing two friends getting killed by massive shark bites (as well as Richard's shark encounter) they all choose to swim away from the island together; even though Sal and Richard used a boat to get the mainland carrying multiples bags of supplies. The newcomers also arrived with multiple kayaks which Richard was aware of before seeing them all get shot.