Plot hole: The whole problem with the teleporter occurs when fly DNA is mixed in with Seth Brundle's DNA, starting his transformation into the Brundlefly. Brundle is on a hiding to nothing from the word go, and the fly is irrelevant. Humans are a walking talking mass of foreign DNA - we are host to one trillion bacteria all of which has a complete compliment of DNA, as do various tiny mites that live in our hair follicles and all sorts of single cell organisms in our gut. If the transporter serves to mix the DNA of all living creatures which are in the transporter pod at the time Brundle would turn into a half-man, half-bacteria. Incidentally, DNA from a bacteria, an amoeba or a hair follicle mite would be just as 'compatible' with human DNA as that from an insect. It's quite a simple chemical, really.
Continuity mistake: In the first act, two of the seven Hoosiers leave the team after Hackman takes over as coach. Shortly after, one of the players reluctantly returns, bringing the total to six. The seventh member, "Buddy," is never shown returning, yet halfway through the film you start seeing him again in the games.
Factual error: At the very beginning of the film, Gunny Highway learns that he's being reassigned to the 2nd Marine Division. The 2nd Division, located at Camp Lejeune, North Carolina, is situated on the NC coast; there are no mountains in the immediate vicinity. However, when the Gunny trains his platoon, he does so in the hills of another Marine training camp located in California. There is a big difference between California and North Carolina.
Continuity mistake: When Tiger and Fievel are doing their musical piece, Tiger wipes off the mirror and they appear the same size. When he lays out in front of the mirror, singing the line "We'll be there to pick each other off the floor", he places his head next to the cage bottom, still laying on the floor between them. In the mirror, however, that cage bottom is not reflected at all. (00:57:30)Garlonuss
Factual error: Cruise is breaking and if you watch the eight ball after the break it's following the 5 into a pocket at the end of the table closest to Tom. Now the 8 ball didn't necessarily go in because they focus on the one ball, but in the next frame shot, there's no way it could be at the opposite end of the table like they show. (00:29:20)
Plot hole: Sarah breaks a mirror in frustration by throwing something against it. Then she buries her face in her arms and sobs. It remains a mystery how she managed to cut her hand so bad that it needed to be fixed with five stitches, as she isn't even seen picking up the pieces. (00:59:15)NancyFelix
Continuity mistake: During Kevin Bacon's race with fellow messenger, the scenes shift back and forth from New York to San Francisco. In one city, he's on a fixed gear (no freewheel on back wheel) and when the race is taking place in the other city, he's riding a single-speed. Basically, the cityscape and bicycles switch from scene to scene.