Plot hole: They're in the Clam complaining that they can't drink when they make the revelation that Brian can because he's technically 56. But Quagmire should be able to drink, as in a much earlier episode, he's revealed to be over 60.
Continuity mistake: When Team Rocket takes off in the boat, it sinks. Their pokeballs float away, and Jessie says "Arbok and Lickitung are floating away!" But she doesn't catch Lickitung until Princess Versus Princess (Season 1, Episode 52).
Continuity mistake: Steve receives a Rowflux and five containers of protein powder. He takes one of the containers leaving only four still on the floor. In a subsequent scene, Steve is still holding the container but now five containers can be seen behind him, giving him six containers altogether.
Continuity mistake: This is a mistake for the introduction from seasons 2-20 (1991-2009). When Homer screams, he turns round. You see this in a wide shot. There are no boxes to the right of the door in the garage. However, two just appear out of thin air when he runs through the garage. (00:01:50)
Continuity mistake: When the two factions of Hondo's pirates are fighting each other, the ones who sided with Maul and Savage are using blasters that fire red bolts, while the ones that stuck with Hondo shoot blue bolts. When Hondo persuades the traitors to work for him again and they attack the two Sith, all of the pirates' blasters are now firing blue bolts. This is Star Wars, not G.I. Joe, and weapons don't just change colour like that.
Continuity mistake: Season 4, episode 10 "Ben 10 vs. The Negative 10, Part 2": When the Forever King makes his announcement "Nothing will stop this little home-coming", he stands outside the Mount Rushmore base on bare soil. But in the scene where Max reviews the recording of this speech, all of a sudden we find the Forever King standing on a neatly tiled floor.